hate (someone's) living guts

Translations
ненавидеть (кого-то) до мозга костей
She hates his living guts ever since the incident.
Она ненавидит его до мозга костей с тех пор, как это произошло.
Definitions
To intensely dislike or despise someone; to have a very strong feeling of hatred toward a person, often expressed in a dramatic or exaggerated way.